Changes between Version 7 and Version 8 of xQTLIntroduction


Ignore:
Timestamp:
2012-02-14T15:35:43+01:00 (12 years ago)
Author:
jvelde
Comment:

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  • xQTLIntroduction

    v7 v8  
    33= [wiki:xQTL xQTL workbench] - Introduction =
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    5 xQTL workbench is a scalable web system for the integrated mapping of thousands of quantitative trait loci (QTLs) at multiple levels:
     5xQTL workbench is a scalable web platform for the mapping of quantitative trait loci (QTLs) at multiple levels: for example gene expression (eQTL), protein abundance (pQTL), metabolite abundance (mQTL) and phenotype (phQTL) data. Popular QTL mapping methods for model organism and human populations are accessible via the web user interface. Large calculations scale easily on to multi-core computers, clusters, and Cloud. All data involved can be uploaded and queried online: markers, genotypes, microarrays, NGS, LC-MS, GC-MS, NMR, etc. When new data types come available, xQTL workbench is quickly customized using the Molgenis software generator.
    66
    7 * Gene expression (eQTL)
    8 * Protein abundance (pQTL)
    9 * Metabolite abundance (mQTL)
    10 * Phenotype (phQTL) levels
     7== Availability ==
     8xQTL workbench is free and open source software, made available under the LGPLv3 license. xQTL workbench runs on most platforms, including Linux, Mac OS X and Windows. xQTL workbench can be rapidly customized using the Molgenis toolkit. See: MolgenisGuide
    119
    12 Main features:
    13 * Popular QTL mapping methods are accessible via the web user interface
    14 * Large calculations scale easily on to multi-core computers, clusters, and cloud
    15 * All data involved can be uploaded and queried online:
    16  * Markers
    17  * Genotypes
    18  * Microarrays
    19  * NGS
    20  * LC-MS
    21  * GC-MS
    22  * NMR
    23 * When new data types come available, xQTL workbench can be rapidly customized using the Molgenis toolkit. See MolgenisGuide.
     10== Contributors ==
     11(c) 2011 - Groningen Bioinformatics Centre & Genomics coordination centre:
     12* Danny Arends [http://www.dannyarends.nl website]
     13* K. Joeri van der Velde [http://www.molgenis.org/wiki/GccStart GCC]
     14* Pjotr Prins [http://www.thebird.nl website]
     15* Karl W. Broman [http://www.rqtl.org R/qtl]
     16* Steffen Möller [http://eqtl.berlios.de/ TIQS]
     17* Ritsert C. Jansen [http://www.rug.nl/fmns-research/bioinformatics/index GBIC]
     18* Morris A. Swertz [http://www.molgenis.org/wiki/GccStart GCC]
    2419
    25 xQTL workbench can be rapidly customized using the Molgenis toolkit. See MolgenisGuide.
     20== Citing us ==
     21
     22Please cite:
     23
     24''xQTL workbench: a scalable web environment for multi-level QTL analysis''[[BR]]
     25Danny Arends; K. Joeri van der Velde; Pjotr Prins; Karl W. Broman; Steffen Moller; Ritsert C. Jansen; Morris A. Swertz[[BR]]
     26Bioinformatics 2012; doi: 10.1093/bioinformatics/bts049